Tax Services for Massachusetts Tech & Biotech Companies - KeyCMS Accounting

Tax Services for Massachusetts Tech & Biotech Companies

As Massachusetts is home to the world’s leading technology and biotechnology companies, rapid innovation creates complex tax challenges. Our specialized tax services help technology and life sciences organizations reduce risk, accelerate growth, and capture every available incentive.

Why Partner With a Tax Firm That Understands
Tech & Biotech?

Industry-Specific Expertise

A general tax advisor may not understand the nuances of software development, clinical trials, FDA pathways, or IP creation. A specialized firm knows the rules, terminology, and tax treatments unique to tech and biotech.

Maximizing R&D Tax Credits

Tech and biotech companies often leave money on the table. Industry-focused firms know how to identify eligible projects, quantify qualified expenses, and defend claims during audits.

Navigating Complex Funding Structures

From venture capital and SAFE notes to NIH/NSF grants, tech and biotech companies deal with unique funding types. A specialist knows how each impacts tax liabilities and planning.

Expertise in Equity Compensation

Stock options, RSUs, ISOs/NSOs, and founder shares require careful planning. Industry-aware advisors help avoid unexpected tax surprises for both the company and employees.

Our Specialty Tax Services

R&D Tax Credits

  • Comprehensive qualification studies
  • Technical interviews with engineers & scientists
  • Audit-ready documentation
  • Startup-friendly R&D credit options

Tax Planning for Equity & Compensation

  • 83(b) strategy review
  • ISO/NSO tax analysis
  • Executive compensation modeling
  • Exit & acquisition planning

State & Local Tax (SALT) for Growing Companies

  • Multi-state nexus assessments
  • Sales & use tax compliance
  • Payroll tax and remote-worker guidance
  • Massachusetts apportionment methods

Biotech-specific tax support

  • Orphan drug credit optimization
  • Capitalization and Amortization of R&D under §174
  • Tax treatment of clinical trial expenses
  • Support for NIH- and NSF-funded research

Corporate Tax Compliance & Advisory

  • Federal and Massachusetts corporate returns
  • ASC 740 tax provision support
  • Transaction tax advisory services
  • Entity structuring for startups to enterprise-level firms

Who We Serve

Early-stage startups and venture-backed firms

Established technology companies scaling across states

Biotech and pharmaceutical developers

Medical device companies

AI, robotics, and software firms

Research labs and contract research organizations (CROs)

Why Massachusetts Tech & Biotech
Leaders Choose Us

Deep industry expertise in emerging technologies and life sciences

Proven success in capturing millions in tax savings from R&D and state incentives.

Audit-ready methodologies that stand up to scrutiny

Transparent pricing and startup-friendly engagement models.

Advisory support that scales with your business-from seed to IPO

Get Your Free Consultation

Let’s unlock every opportunity available to your Massachusetts tech or biotech business.

Frequently Asked questions

The most common are the Massachusetts R&D Tax Credit and the Federal R&D Credit, but companies may also be qualified for other incentives such as the Life Sciences Tax Incentive Program, investment tax credits, and payroll tax offsets for qualified startups.
If your engineers, developers, or scientists are working to create or improve products, software, processes, or formulas through technical experimentation, you likely qualify. We conduct detailed technical interviews to confirm eligibility.
Yes. Startups that have little or no taxable income can often apply R&D credits against payroll taxes, making the benefit immediately valuable.
Massachusetts offers both a volume-based and incremental R&D credit. The new federal rules require the capitalization and amortization of R&D costs under IRC §174-a major shift with which many technology and biotechnology firms will need assistance in adapting.
We prepare audit-ready documentation for every engagement and provide full support during IRS or Massachusetts audits, including technical write-ups, cost substantiation, and direct representation.

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Benefits you get from us

  • Up to date accounts

  • Accurate accounts

  • Cost savings

  • Data Security